Promethazine with codeine syrup is indicated with the short term aid of coughs and higher respiratory indications associated with allergy or even the widespread chilly.
This medication continues to be prescribed in your recent issue only. Never use it afterwards for one more issue Except told to do so by your physician. A distinct medication can be vital in All those scenarios.
Unresponsive Cough The dosage of Promethazine HCl and Codeine Phosphate Oral Solution shouldn't be enhanced if cough fails to reply; an unresponsive cough really should be reevaluated in 5 days or faster for doable underlying pathology, for example overseas entire body or reduced respiratory tract disorder [see Dosage and Administration (two.three)].
This medication could lead to hurt and Demise if it is taken by other Grownups, small children, or Animals. It is crucial to get rid of the medication once you not need it or it is actually expired. You can do this in two approaches:
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However it can help Many individuals, this medication includes a hazard for abuse and could at times bring about habit. This danger might be larger if you have a substance use dysfunction (for instance overuse of or addiction to prescription drugs/Liquor).
Neuroleptic malignant syndrome (NMS) which may result in Loss of life. Show you healthcare provider without delay if you have any of the following indicators of NMS:
Nonetheless, codeine needs to be administered only less than shut supervision to clients with a history of drug abuse or dependence.
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Lifetime-threatening respiratory depression and Demise have occurred in kids who acquired codeine; most conditions adopted tonsillectomy and/or adenoidectomy, and a lot of of the kids experienced proof of currently being an extremely-immediate metabolizer of codeine as a result of a CYP2D6 polymorphism. (5.three) Promethazine HCl and Codeine Phosphate Oral Remedy is contraindicated in small children young than twelve years of age As well as in small children youthful than eighteen years of age following tonsillectomy and/or adenoidectomy.
Cautiously evaluate the dose employing a Unique measuring system/spoon. Don't make use of a home spoon since you may well not get the correct dose.
Codeine has become reported to indicate no evidence of carcinogenicity or mutagenicity in a number of take a look at techniques, including the micronucleus and sperm abnormality assays and also the Salmonella assay. Promethazine was nonmutagenic inside the Salmonella examination program of Ames.
Keep in mind that this medication has long been prescribed since your medical doctor has judged the advantage to you is greater than the potential risk of Unwanted effects. A lot of people applying this medication would not have major Negative effects.
When medical professionals prescribe codeine-that contains medicine, they must pick the cheapest helpful dose for the shortest length of time and will inform their people about these risks and also the indications of morphine overdose (see PRECAUTIONS - Nursing Mothers).